You’ve undoubtedly
heard of chlorophyll, and you probably know that plants couldn’t without it.
But what is chlorophyll exactly, and are there chlorophyll benefits for humans?
As we learned back in
science class, chlorophyll is a type of plant pigment responsible for the
absorption of light in the process of photosynthesis, which creates energy. So
why is it important for humans beyond sustaining plant life? Turns out,
chlorophyll is linked to natural cancer prevention, blocks carcinogenic effects
within the body and protects DNA from damage caused by toxic molds like
aflatoxin — very similar to way in which chlorophyll-rich chlorella has
anticancer effects.
And that’s just one of
the five major chlorophyll benefits for human health, all of which help cleanse
the body and allow it to function at an optimal level.
5 Proven Chlorophyll
Benefits
1. Helps Fight Cancer
Studies have found
that chlorophyll and liquid chlorophyllin —a similar semi-synthetic mixture
made in laboratories to be used in supplements, often called liquid chlorophyll
— can bind to potential carcinogens and interfere with how they’re absorbed
within the human gastrointestinal track. This helps stop them from being
circulated throughout the body and reaching susceptible tissues, such as those
within the joints or heart.
Studies done by the
Linus Pauling Institute at Oregon State University showed that chlorophyllin
and chlorophyll were equally effective at blocking uptake of aflatoxin-B1 in
humans and decreasing biomarkers of aflatoxin-induced DNA damage. (1) Findings
from several other animal and human studies suggest that these effects help
lower the risk for certain types of cancers, including liver and colon cancer.
The mechanism by which
chlorophyll decreases the risk for cancer development and cleanses the liver is
by interfering with the metabolism of chemicals’ procarcinogen, which must
first be metabolized in order to damage DNA. Within the human body, enzymes
called cytochrome P450 activate procarcinogens and turn them into active
carcinogens, which go on to attack healthy cells. This means inhibiting their
effects can help stop the process of chemically induced cancers.
Diets that are high in
red meat and low in green vegetables are associated with increased colon cancer
risk. This is sometimes blamed on toxins released from cooked meat, including
one called haem, which increases colonic cytotoxicity and epithelial cell
proliferation. Recently, some research suggests that human colon cancer cells
experience “cell arrest” when exposed to chlorophyllin due to inhibition of
ribonucleotide reductase activity, which helps protect DNA and boosts synthesis
and repair. This is why in recent years ribonucleotide reductase activity has
come under investigation for naturally treating cancer and its many side
effects.
In 2005, the
Wageningen Centre for Food Sciences in the Netherlands studied whether green
vegetables could inhibit the unfavorable effects of haem within the colon. Rats
were fed either a control diet high in haem or a similar diet supplemented with
chlorophyll for 14 days. The results showed that the rats consuming haem
experienced about eight times the amount of cytotoxicity of the colon compared
to the beginning of the study. The rats given chlorophyll supplements were
significantly protected from formation of the cytotoxic haem metabolites, which
made the researchers conclude that green vegetables may decrease colon cancer
risk because chlorophyll prevents the cytotoxic and hyperproliferative colonic
effects of dietary toxins like haem. (2)
2. Improves Liver
Detoxification
Another way by which
chlorophyll might protect healthy cells and bodily tissue is by increasing
phase II biotransformation enzymes. These promote optimal liver health and
therefore the body’s natural elimination of potentially harmful toxins. Some
early studies involving animals show that chlorophyllin may reduce the risk for
aflatoxin-induced liver damage or liver cancer by increasing activity of these
phase II enzymes and removing bodily toxins. (3)
Aflatoxin-B1 (AFB1) is
associated with increased risk of hepatocellular carcinoma and liver cancer
because it’s metabolized to a carcinogen that causes cellular mutations. In
animal studies, supplementing with chlorophyllin at the same time as consuming
high amounts of dietary AFB1 significantly reduced the amount of DNA damage
that developed. This is especially important for people who consume high
amounts of grains or legumes, such as those living in underdeveloped nations.
In China, a randomized,
placebo-controlled intervention trial involving 180 adults with a high risk of
hepatocellular carcinoma and chronic hepatitis B infection gave participants
either 100 milligrams of chlorophyllin or a placebo before meals three times
daily. After 16 weeks of taking chlorophyllin, AFB1 levels dropped an average
of 55 percent more in those taking chlorophyllin compared tothose taking the
placebo, suggesting chlorophyll benefits liver health in a useful and safe way.
(4)
3. Speeds Up Wound
Healing
Chlorophyllin seems to
slow the rate at which harmful bacteria reproduce, making it beneficial for
wound healing and preventing infections. Since about the 1940s, cholorphyllin
has been added to certain ointments used to heal persistent open wounds in humans,
such as a vascular ulcer and pressure ulcer. It’s been found to help lower
inflammation caused by injuries or wounds, promote healing, and even control
odors caused by bacteria accumulation. (5)
4. Improves Digestion
and Weight Control
Another way that
chlorophyll improves detoxification is by speeding up waste elimination,
balancing fluid levels and reducing cases of constipation. Additionally,
preliminary research shows chlorophyll benefits the metabolism and increases
the likelihood of success with weight-loss efforts.
A 2014 study conducted
by the Department of Experimental Medical Science at Lund University in Sweden
found that chlorophyll supplements taken along with a high-carbohydrate meal
decreased feelings of hunger, elevated cholecystokinin levels and helped
prevent hypoglycemia in overweight women. (6)
Prior to the study,
previous research had shown that chlorophyll taken in the form of thylakoid
supplements helped balance the release of hormones that make us feel fuller,
including cholecystokinin, ghrelin and insulin. While the studies so far have
mostly looked at the weight-loss effects of chlorophyll taken by rodents,
results suggest that it might help naturally suppress food intake and prevent
body weight gain in humans too. (7)
The small study done
by Lund University observed 20 overweight females eating meals on three
different occasions. The test meals consisted of a high-carbohydrate Swedish
breakfast, taken with or without addition of chlorophyll in the form of
thylakoids. Thylakoids helped suppress hunger and increased secretion of
satiety hormones following food intake, preventing compensational eating later
in the day — which we would expect over time to help with weight loss and
appetite control.
5. Protects Skin
There’s some evidence
that chlorophyll benefits skin healthy due its antiviral effects, allowing it
to help stop the development of cold sores within the mouth or genital area
caused by the herpes simplex virus. Some early studies have found that when
chlorophyll-containing ointment or cream is applied to skin it helps reduce the
number of sores that appear and speeds up healing time, making it a natural
herpes treatment. (8)
Chlorophyll might also
be able to protect the skin from shingles, reducing symptoms like painful
sores, plus lower the risk for skin cancer. Injecting chlorophyll directly into
the skin or applying it via lotion has been found to help reduce the recurrence
of cancerous cells in people with basal cell carcinoma, a very common type of
skin cancer.
How Chlorophyll Works
Chlorophyll can be
found in all green plants. This includes leafy greens and other veggies we
commonly eat, plus certain types of algae or bacteria. While chlorophyll is
totally natural, a similar semi-synthetic mixture called chlorophyllin is made
in laboratories to be used in supplements, such as those marketed as “liquid
chlorophyll.” These supplements have been in existence for more than 50 years
and are commonly used to treat skin wounds, body odor, digestive problems and
other health concerns with practically no side effects at all.
You probably know that
plants couldn’t live without chlorophyll, but maybe you’re wondering what kind
of chlorophyll benefits there are for humans. As mentioned, chlorophyll is
linked to natural cancer prevention, blocks carcinogenic effects within the
body and protects DNA from damage caused by toxic molds like aflatoxin.
Chlorophyllin supplements are believed to help neutralize oxidants, which means
they effectively decrease oxidative damage caused by factors like a poor diet,
chemical carcinogens, UV light exposure and radiation.
The Tropical Botanic
Garden and Research Institute in India has found that chlorophyll from fresh
green leaves has potent anti-inflammatory activities against dangerous bacteria
and other environmental toxins. It helps turn off a pro-inflammatory cytokine
called lipopolysaccharide-induced TNF-α, making it a promising treatment option
for inflammation and related chronic diseases that conventional medicine has failed
to control. (9)
Another one of the big
chlorophyll benefits might surprise you. It seems to help promote weight loss
by controlling appetite hormones and improving obesity-related risk factors,
all without the scary side effects of most commercial weight-loss supplements.
(10)
The chlorophyll
definition is “the green substance in plants that makes it possible for them to
make food from carbon dioxide and water.” There are two main forms of
chlorophyll found in nature: chlorophyll-a and chlorophyll-b. There is a small
difference between the two types, basically that each absorbs light from the
sun at slightly different wavelengths. In natural plants containing
chlorophyll, there is a ratio of 3:1 cholorophyll-a (a bluish-black solid) to
cholorophyll-b (a dark green solid), which both work together to reflect the
dark green pigment that’s visible to the human eye.
Plants and algae use
chlorophyll to trap light from the sun that’s needed for photosynthesis, which
is why chlorophyll is considered a “chelate.” In fact, it’s considered the
single most important chelator found in nature, since it gives plants energy,
which then give us energy.
Chlorophyll-a and
chlorophyll-b are both fat-soluble, meaning they won’t dissolve in water and
are absorbed by the digestive system best when they’re consumed with at least a
small amount of fat (lipids). Synthetically made chlorophyllin is soluble in
water, however, which means you can take a chlorophyllin supplement without
needing to eat a source of fat to fully dissolve it.
On a molecular level,
the structure of chlorophyll is very similar to heme, which is a part of
hemoglobin present in human blood. Heme, which is what makes blood appear
bright red once exposed to oxygen, is bound to proteins forming hemoglobin.
Hemoglobin carries oxygen to the lungs and other respiratory surfaces to be
released into tissues throughout the body.
The primary reason
chlorophyll is considered a superfood is because of its strong antioxidant and
anticancer effects. Chlorophyll benefits the immune system because it’s able to
form tight molecular bonds with certain chemicals that contribute to oxidative
damage and diseases like cancer or liver disease. These are called
“procarcinogens” substances, and some of the types that chlorophyll can help
block include: (11, 12)
polycyclic aromatic
hydrocarbons found in tobacco smoke
heterocyclic amine
toxins found in meat cooked at high temperatures
food-born toxins,
including aflatoxin-B1, a type of dietary mold (also called a fungus) found in
many grains and legumes, such as corn, peanuts and soybeans. When processed and
included in refined foods, I like to call these “metabolism death foods“
UV light that can
cause skin damage in excess
How to Get More
Chlorophyll: Top Chlorophyll Food Sources
What’s the best way to
detox using chlorophyll? The very best sources of chlorophyll found on the
planet are green vegetables and algae. Here are some of the top food sources to
incorporate into your diet to experience all of the chlorophyll benefits.
Leafy green vegetables:
Green veggies like kale, spinach or Swiss chard get their signature pigment
from a high concentration of chlorophyll. Ideally, every day you should consume
some variety of leafy greens as part of your recommended five to seven servings
of vegetables, but if you find this difficult consider juicing greens instead.
Raw or lightly cooked
foods: An interesting finding published by the Institute of Food Technologies
is that chlorophyll content is decreased when green veggies are cooked, thawed
after being frozen or when they start to spoil. For example, the amount of
chlorophyll in spinach was decreased by about 35 percent after it was thawed
and another 50 percent after it was boiled or steamed. (13) To consume the most
chlorophyll from your diet, try eating more of a raw food diet or lightly
cooking your veggies using low temperatures.
According to Oregon
State University, here is a list of the chlorophyll content (bound to
magnesium) of selected raw vegetables:
1 cup spinach: 23.7
milligrams
1/2 cup parsley: 19.0
milligrams
1 cup watercress: 15.6
milligrams
1 cup green beans: 8.3
milligrams
1 cup arugula: 8.2
milligrams
1 cup leeks: 7.7
milligrams
1 cup endive: 5.2
milligrams
1 cup sugar snap peas:
4.8 milligrams
1 cup Chinese cabbage:
4.1 milligrams
Chlorella: A type of
blue-green algae that’s native to parts of Asia, chlorella is packed with
chlorophyll in addition to many phytonutrients, amino acids, vitamins and
minerals. Just like chlorophyll itself, chlorella is tied to healthy hormonal
balance, detoxification, cardiovascular health, and lower levels of
inflammation, blood pressure and cholesterol. In addition to consuming the
algae, for convenience sake you can also take extracted chlorella supplements
in either powder or tablet form.
Chlorophyllin
supplements: Green algae like chlorella are often used to make chlorophyllin,
which is found in most supplements. That’s because natural chlorophyll is not
very shelf-stable and is prone to degradation, making it hard to consume and
very expensive. Oral doses of chlorophyllin supplements taken in amounts about
100–300 milligrams per day (usually divided into three doses) have been used to
safely treat conditions with almost no side effects for over five decades.
Liquid chlorophyll and
other common sources: Supplemental chlorophyll can be found in herbal
treatments, including alfalfa (Medicago sativa) and silkworm droppings. If you
have access to liquid chlorophyll, try adding a few drops to a glass of water
once or twice a day. It will turn your water bright green, although rest
assured it doesn’t taste as bad as it might look and might help give you a
little boost in energy when sipped throughout the day.
Can Chlorophyll Ever
Cause Toxicity?
Because it’s completely natural, chlorophyll and chlorophyllin are not known to
be toxic. In fact, over the past 50 years there have been practically no toxic
effects attributed to their consumption, even in people with weak immune
systems, such as those healing from cancer.
While the risk for toxicity is extremely low, chlorophyllin supplements might
cause minor side effects like green discoloration of urine or feces, temporary
discoloration of the tongue, or mild indigestion/diarrhea. These usually go
away quickly and are only caused by supplemental chlorophyllin use, as opposed
to eating foods that naturally contain chlorophyll.
In pregnant women, chlorophyll or chlorophyllin supplements haven’t been
researched very much, so at this time it’s not recommended that they’re used
during pregnancy or when breast-feeding.
One interaction to keep in mind is that certain medications that increase
sensitivity to sunlight (photosensitizing drugs) can interact with chlorophyll.
This means taking these medications along with chlorophyll can increase
sensitivity to sunlight even more and make you susceptible to burns. Use
chlorophyll supplements carefully if you take photosensitive drugs or are
especially prone to sunburns, blistering or rashes when you’re exposed to UV
light.
Final Thoughts on Chlorophyll Benefits
Chlorophyll benefits
include helping fight cancer, improving liver detoxification, speeding up wound
healing, improving digestion and weight control, and protecting skin health.
The primary reason
chlorophyll is considered a superfood is because of its strong antioxidant and
anticancer effects. Chlorophyll benefits the immune system because it’s able to
form tight molecular bonds with certain chemicals that contribute to oxidative
damage and diseases like cancer or liver disease.
The very best sources
of chlorophyll found on the planet are green vegetables and algae. Here are
some of the top food sources to incorporate into your diet to experience all of
the chlorophyll benefits. This includes green leafy veggies like kale, spinach
and Swiss chard. Cooking these foods decreases the nutrient content and lowers
the chlorophyll benefits you get, so eat them raw or lightly cooked to preserve
the nutrients.
Consuming chlorella,
chlorophyllin supplements and liquid chlorophyll are also ways to get
chlorophyll benefits.
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